Litsty PEN3-1 3D wiew

PenBase
Penaeidin database

 

PenBase is a curated database devoted to Penaeidins

     Antimicrobial peptides are major components of innate immunity that have been conserved in evolution and found in different phyla of the plant and animal kingdom. Antimicrobial peptides are often small cationic molecules widely distributed in the whole living kingdom where they participate to host defence reactions against invading microorganisms. They are known to be involved in the innate immune response of vertebrate, invertebrate and plant species, and they are thought to be essential in organisms which lack adaptive immunity.
     Penaeidins are members of a family of antimicrobial peptides, originally isolated from the shrimp Litopenaeus vannamei, which present both Gram-positive antibacterial and antifungal activities (Destoumieux et al, 1997). Penaeidins appear to be a family of antimicrobial peptides ubiquitous among penaeid shrimps where they are major actors of the immune response (Bachère et al., 2004).

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     PenBase provides comprehensive information about penaeidin properties, function, diversity and nomenclature.
     PenBase contains a Database section that lists all known penaeidins by subgroup or shrimp species.

When referencing PenBase, please use the following PenBase Reference:
PenBase, the shrimp antimicrobial peptide penaeidin database: Sequence-based classification and recommended nomenclature. Gueguen Y., J. Garnier, L. Robert, M.P. Lefranc, I. Mougenot, J. de Lorgeril, M. Janech, P.S. Gross, G.W. Warr, B. Cuthbertson, M.A. Barracco, P. Bulet, A. Aumelas, Y. Yang, D. Bo, J. Xiang, A. Tassanakajon, D. Piquemal, E. Bachère (2005). Dev Comp Immunol. Volume 30, Issue 3 , 2006, Pages 283-288